Indigo Naturalis has a variety of pharmacological activities, such as anti-inflammatory, antioxidant, antibacterial, and immunomodulatory properties, which contribute to its effectiveness in treating conditions like psoriasis

Clinical studies report that Indigo naturalis offers significant relief for psoriasis symptoms, including erythema, scales, and pruritus. The overall cure rate in early clinical observations reached 69.6% for psoriasis patients

Indigo naturalis helps reduce inflammation by down-regulating inflammatory markers such as TNF-α and IL-6, critical factors in the progression of psoriasis, via the TLRs/NF-κB and AhR pathways

Indigo naturalis inhibits the excessive proliferation of keratinocytes, which is a key aspect of psoriasis management

Indigo naturalis is known for its long history of use in traditional medicine with minimal adverse reactions, making it a safe option for long-term psoriasis management, although mild, reversible side effects such as skin itching have been reported in a few cases

Indigo naturalis demonstrates potential as an immune modulator, which makes it beneficial for autoimmune diseases, including psoriasis, by balancing inflammatory responses and regulating immune-related skin functions"

Studies show that indigo naturalis not only acts as a powerful antioxidant, neutralizing free radicals, but also provides protection from oxidative stress in skin cells, which is essential for inflammatory skin conditions like psoriasis"